Assessing the effect of omega-3 fatty acid combined with vitamin D3 versus vitamin D3 alone on estradiol levels: a randomized, placebo-controlled trial in females with vitamin D deficiency.

Clin Pharmacol · 2019 · PMC6366354 · PMID 30787641

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marginally significantno p-value reported

36 After four weekly doses of 28,000 IU VD3, there was a marginally significant reduction in luteal E2 levels by 3% per 10 nmol/L increase of 25OHD, and this may be the mechanism by which VD protects against breast cancer.

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