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The Impact of (the Concept of) Treatment-Resistant Depression: An Opinion Review.

Int J Neuropsychopharmacol · 2019 · PMC6368367 · PMID 29961822

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highly significantno p-value reported
Indeed, considering physician or patient guess (on which treatment they guessed they were) gave highly significant differences between treatment arms: the highest remission rates (43% vs 6% for placebo) were found with sertraline when the physician guessed the patient was on sertraline and with hypericum (37% vs 22% for placebo) when the patient guessed he or she was on hypericum ( Chen et al., 2011 , 2015 ).

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