Flavones hydroxylated at 5, 7, 3' and 4' ameliorate skin fibrosis via inhibiting activin receptor-like kinase 5 kinase activity.

Cell Death Dis · 2019 · PMC6370799 · PMID 30741930

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a decreasing trendno p-value reported

This assay showed a decreasing trend of the emission ratio induced by luteolin, quercetin or myricetin in a dose-dependent manner, indicating the competitive binding of the compounds with ALK5 (Fig. 7a ).

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