Although the difference between active and sham group was only close to significance immediately after the stimulation, active group showed clinical benefit overtime and significance difference was found after 4 months (-36.96%) and a trend for reduction in length of migraine episodes (in hours) of 88.75%.
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Treating Chronic Migraine With Neuromodulation: The Role of Neurophysiological Abnormalities and Maladaptive Plasticity.
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