Synergistic action of dual IGF1/R and MEK inhibition sensitizes childhood acute lymphoblastic leukemia (ALL) cells to cytotoxic agents and involves downregulation of STAT6 and PDAP1.

Exp Hematol · 2018 · PMC6371922 · PMID 29656114

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highly significantno p-value reported

This identified a marked ( r > 0.6) and highly significant expression codependency between STAT6 and PDAP1 ( Figure 3 B).

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