Barely Significant
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Circular RNAs in immune responses and immune diseases.

Theranostics · 2019 · PMC6376182 · PMID 30809295

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highly significantno p-value reported
Hence, early diagnosis is highly significant and essential for immune disease therapy.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.