The rs61742690 (S783N) single nucleotide polymorphism is a suitable target for disrupting BCL11A-mediated foetal-to-adult globin switching.

PLoS One · 2019 · PMC6377191 · PMID 30768627

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highly significantno p-value reported

Highly significant (±100% variation) deviation in the interface energy due to the amino acid substitution was observed for four interactions ( Fig 6 ).

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