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Alteration of mRNA abundance, oxidation products and antioxidant enzyme activities during oocyte ageing in common carp Cyprinus carpio.

PLoS One · 2019 · PMC6386366 · PMID 30794661

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a decreasing trendno p-value reported
Our results indicated that the relative mRNA level of igf2 showed a decreasing trend to 6 HPO and HPS and then increased until the complete loss of egg viability occurred.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.