Barely Significant
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Area under the forced expiratory flow-volume loop in spirometry indicates severe hyperinflation in COPD patients.

Int J Chron Obstruct Pulmon Dis · 2019 · PMC6388784 · PMID 30863041

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an increasing trendno p-value reported
Both differences showed an increasing trend with the means, while the variability did not show a consistent pattern.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.