Synaptic proteins in CSF as potential novel biomarkers for prognosis in prodromal Alzheimer's disease.

Alzheimers Res Ther · 2018 · PMC6389073 · PMID 29370833

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.1200

boldest claim

The sentences

borderline significantp = 0.05actually significant

VGF showed a different pattern with evidently lower values in patients with AD dementia than in control subjects (β = −0.46 [SE 0.19]) and in patients with MCI (−0.93 [SE 0.22]), whereas the difference between patients with MCI and control subjects was only borderline significant (β = 0.47 [SE 0.20], p = 0.05).

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just above the level of significancep = 0.12not close (p > 0.1)

The overall interaction between diagnosis and protein was just above the level of significance ( p = 0.12); however, to be able to compare this analysis with the one with baseline diagnosis, we also stratified this analysis according to protein.

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