Impaired Interneuron Development in a Novel Model of Neonatal Brain Injury.

While human glutamatergic neurogenesis is complete by 28 weeks of gestation ( Malik et al., 2013 ), GABAergic progenitors persist in the ganglionic eminences through at least 35 weeks of gestation and continue to migrate into the cortex throughout the perinatal period ( Sanai et al., 2011 ; Arshad et al., 2016 ; Paredes et al., 2016 ), suggesting that perinatal insults may be significant environmental factors predisposing preterm survivors to psychiatric disorders.

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