The molecular basis for an allosteric inhibition of K<sup>+</sup>-flux gating in K<sub>2P</sub> channels.

Elife · 2019 · PMC6391080 · PMID 30803485

Europe PMC DOI

hedged sentence

0.0010

closest p · 0.0× alpha

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boldest claim

The sentences

highly significantp<0.001actually significant

We do not agree that the voltage‐dependence is to shallow to calculate and the quantification that we have provided clearly showed a highly significant (p<0.001) voltage‐dependent block by bupivacaine, with a 2.5‐fold more pronounced inhibition at +70 mV compared to ‐70 mV, as analyzed in Figure 1D.

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