Prophylactic lactoferrin for preventing late-onset sepsis and necrotizing enterocolitis in preterm infants: A PRISMA-compliant systematic review and meta-analysis.

Medicine (Baltimore) · 2018 · PMC6392939 · PMID 30170397

Europe PMC DOI

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a decreasing trendP < .01actually significant

Lactoferrin could shorten time to reach full enteral feeding (weighted mean difference [WMD] = −2.11, 95% CI −3.12 to −1.10; P < .01) and showed a decreasing trend of duration of hospitalization (WMD = −1.69, 95% CI −6.87 to 3.50; P < .01; I = 95%).

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