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Successful treatment of malignant pheochromocytoma with sacrum metastases: A case report.

Medicine (Baltimore) · 2018 · PMC6393136 · PMID 30170467

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may be significantno p-value reported
As the tumor is highly vascular, there may be significant intraoperative blood loss which may influence the hemodynamic instability and necessitate blood transfusion.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.