Aβ Oligomer Elimination Restores Cognition in Transgenic Alzheimer's Mice with Full-blown Pathology.

We observed a tendency for a reduction in gliosis after RD2 treatment, which was close to being significant in the cortex of RD2-treated mice (Fig. 2 b; GFAP staining: unpaired one-tailed Student’s t test, cortex n.s. p = 0.064, hippocampus n.s. p = 0.3) (Fig. 2 c; CD11b staining: unpaired one-tailed Student’s t test, cortex n.s. p = 0.051, hippocampus n.s. p = 0.28).

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