E-cadherin-deficient cells have synthetic lethal vulnerabilities in plasma membrane organisation, dynamics and function.

In contrast, the overall density distribution of 496 protein kinases in the siRNA screen showed a small but highly significant shift ( p < 2.2 × 10 −16 ) towards synthetic lethality with the peak of the density distribution at 0.95 (Fig. 1 c).

also in 132,142 other papers