32 A highly significant number of PS89 target proteins was assigned to be located in the ER (false discovery rate 5.9×10 −12 ) and described to be involved in cellular homeostasis, in particular cell redox homeostasis (false discovery rate 9.1×10 −7 and 6.7×10 −9 ) ( Figure 2D,E ).
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Targeting the endoplasmic reticulum-mitochondria interface sensitizes leukemia cells to cytostatics.
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