However, the difference between PD patients and controls remained highly significant even following normalization with the geometric mean of NURR1-MAPT-GAPDH .
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Long Non-coding RNAs Associated With Neurodegeneration-Linked Genes Are Reduced in Parkinson's Disease Patients.
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However, the relative RNA expression of these lncRNAs, normalized to relative GAPDH expression levels, did not reveal statistically significant differences between PBMCs derived from PD patients and controls, although a slight trend for reduced expression in patients was observed for all lncRNAs tested ( Figure 5A ).