Comparative risk of new-onset diabetes following commencement of antipsychotics in New Zealand: a population-based clustered multiple baseline time series design.

4 7 8 However, there is an increasing trend to prescribe AP off-label for ailments such as anxiety, insomnia, personality disorders and post-traumatic stress in primary and secondary care. 9–11 It may be perceived as less harmful, however, even low doses of some APs are known to increase the risk of weight gain, 1 12 13 which consequently may increase the risk of T2DM. 14 The comparative risks of different subgroups of APs are not yet known.

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