<i>Pseudomonas aeruginosa Exoprotein</i>-Induced Barrier Disruption Correlates With Elastase Activity and Marks Chronic Rhinosinusitis Severity.

Front Cell Infect Microbiol · 2019 · PMC6400838 · PMID 30873390

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highly significantno p-value reported

There was a highly significant strong correlation between the in vitro elastase activity of P. aeruginosa CIs with mucosal barrier disruption evidenced by increased permeability of FITC-dextrans ( r = 0.95, p = 0.0004) and decreased TEER ( r = −0.9333, P < 0.01) after 4 h of challenge.

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