An Appraisal of the Influence of the Metabotropic Glutamate 5 (mGlu5) Receptor on Sociability and Anxiety.

The lowered active exploration of the conspecific in mice treated with MTEP was accompanied by a marked decrease in object exploration and an increase in locomotor activity during the test, as shown by the distance traveled during the test at 5 min post-injection [ t -test: t (1,24) = 4.56, p < 0.001] ( Figure 3E ) as well as by a statistical trend toward significance at 1 h post injection [ t -test: t (1,22) = 1.77, p = 0.09] ( Figure 3K ).

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