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Reversing the "Risk-Treatment Paradox" of Bleeding in Patients Undergoing Percutaneous Coronary Intervention: Risk-Concordant Use of Bleeding Avoidance Strategies Is Associated With Reduced Bleeding and Lower Costs.

J Am Heart Assoc · 2018 · PMC6404202 · PMID 30376760

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an increasing trendno p-value reported
Furthermore, an increasing trend in risk‐concordant use of BAS was associated with concomitant reducing trends in the incidence of bleeding and hospital costs.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.