Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death.

Nature · 2019 · PMC6405297 · PMID 30760928

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Despite highly significant inverse correlation between NPM-ALK translocation and SQLE expression, modulation of ALK signaling did not affect SQLE expression, suggesting that SQLE may be silenced due to a different mechanism ( Extended Data Fig. 3f-h ).

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