Rare variants in the genetic background modulate cognitive and developmental phenotypes in individuals carrying disease-associated variants.

Genet Med · 2019 · PMC6405313 · PMID 30190612

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marginal significanceno p-value reported

Even though the sample size in the SSC cohort ( n = 8) is small, we hypothesized that this marginal significance compared with 16p11.2 deletion probands from the SSC cohort (Figs. 4a and S 5B ) could be due to differences in clinical ascertainment.

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