Note, when frog is included, we also see a significant enrichment of positively selected downstream genes in mammals relative to sauropsids ( χ 2 = 4.306; P value = 0.047; supplementary table S11 , Supplementary Material online), however this relationship is a weak trend and may be driven by the poor alignments (see supplementary material, Supplementary Material online).
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Contrasting Patterns of Rapid Molecular Evolution within the p53 Network across Mammal and Sauropsid Lineages.
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