The Importance of the Hedgehog Signaling Pathway in Tumorigenesis of Spinal and Cranial Chordoma.

In addition, the expression rate of Shh and GLI 1 raised by the first recurrence, while their expression levels exhibited a decreasing trend in the second recurrence; however, a final interpretation of this event cannot be done because different factors may be involved in this condition, such as the sample size that should be considered in the light of a limitation.

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