Matrix Metalloprotease Generated Fragments of Type VI Collagen Have Serum Biomarker Potential in Cancer - A Proof of Concept Study.

Transl Oncol · 2019 · PMC6411605 · PMID 30856553

Europe PMC DOI

hedged sentences

0.0001

closest p · 0.0× alpha

0.0720

boldest claim

The sentences

highly significantP < .0001actually significant

As shown in Figure 4 , the diagnostic power of C6Ma1 and C6Ma3 was highly significant with an AUROC of 0.90 ( P < .0001) and of 0.87 ( P < .0001), respectively when comparing healthy control to patients with cancer.

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borderline significantP = .072so close (0.05 < p ≤ 0.1)

These findings indicate that PRO-C6 could be prognostic in cancer, which is also supported by the borderline significant association between cancer stage and PRO-C6 levels ( P = .072, when comparing early vs late stage patients).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.