Breadth and depth of working memory and executive function compromises in mild cognitive impairment and their relationships to frontal lobe morphometry and functional competence.

Chi square analyses indicated that this difference in distribution was highly significant. 3.2 Depth of WM/EF impairment in MCI and AD The MCI group demonstrated medium to large ES compared with the EHC group ( Table 2 and Supplementary Fig. 1 ) in Tower test (ES = 0.88), TMT-B (ES = 0.85), TMT B-A (ES = 0.78), letter-number manipulation (ES = 0.71), and One-back accuracy (ES = 0.55).

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