Aneuploidy in Oocytes Is Prevented by Sustained CDK1 Activity through Degron Masking in Cyclin B1.

Dev Cell · 2019 · PMC6416240 · PMID 30745144

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Furthermore, checkpoint signaling may be problematic in larger cells where the ratio of kinetochores to cell volume is low ( Galli and Morgan, 2016 ), a problem likely to be significant in an oocyte that is typically ∼300 times the volume of a mitotic cell.

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