Bias in pharmacoepidemiologic studies using secondary health care databases: a scoping review.

BMC Med Res Methodol · 2019 · PMC6419460 · PMID 30871502

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an increasing trendno p-value reported

An increasing trend in the number of publications concerning the potential limitations of secondary databases was observed over time and across medical research disciplines.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.