4 ), whereas parameters that describe heterogeneity (sum entropy) became significant, or borderline significant (difference entropy, joint entropy), associated with OS (Table 2 , Fig. 5 ).
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Optimal respiratory-gated [<sup>18</sup>F]FDG PET/CT significantly impacts the quantification of metabolic parameters and their correlation with overall survival in patients with pancreatic ductal adenocarcinoma.
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