Decrease in inflammatory biomarker concentration by intervention with selenium and coenzyme Q10: a subanalysis of osteopontin, osteoprotergerin, TNFr1, TNFr2 and TWEAK.

However, after 42 months a highly significant difference between the two groups could be found (60,067 mmol/L vs. 71,632 mmol/L; T = 3.72; P = 0.0003) with a lower concentration in the active treatment group.

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Analyzing the placebo group, a borderline significant increase in the concentration of osteopontin could be seen between six months and 42 months (65,395 mmol/L vs. 71,633 mmol/L; T = 1.90; P = 0.059); however, in the active group no significant change in concentration could be found (65,913 mmol/L vs. 60,067 mmol/L; T = 1.17; P = 0.24).

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