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Efficacy and safety of ivermectin and albendazole co-administration in school-aged children and adults infected with Trichuris trichiura: study protocol for a multi-country randomized controlled double-blind trial.

BMC Infect Dis · 2019 · PMC6421712 · PMID 30885157

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a decreasing trendno p-value reported
Furthermore, this drug has been used for more than three decades and comparison of efficacy measures over time indicates a decreasing trend over time; although resistance has so far not been documented in its use in humans [ 5 ].

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