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Desialylation of platelets induced by Von Willebrand Factor is a novel mechanism of platelet clearance in dengue.

PLoS Pathog · 2019 · PMC6426266 · PMID 30849118

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an increasing trendno p-value reported
In contrast to our current findings, VWF:Ag levels in these children admitted to the ICU with severe dengue showed an increasing trend towards discharge, while levels of VWF:propeptide decreased.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.