borderline significantP = 0.048
When the pattern of duplications was analyzed separately, both effects were maintained (model R 2 = 0.44; gene version : pseudo- F 2, 12 = 1.671, P = 0.034, R 2 = 0.155; antibiotic : pseudo- F 1, 12 = 3.174, P = 0.001, R 2 = 0.147) whereas when the pattern of deletions was analyzed separately, only the cat gene version had a borderline significant effect (model R 2 = 0.33; gene version : pseudo- F 2, 12 = 1.646, P = 0.048, R 2 = 0.183; antibiotic : pseudo- F 1, 12 = 0.929, P = 0.48, R 2 = 0.052).