Assessing CYP2C19 Ontogeny in Neonates and Infants Using Physiologically Based Pharmacokinetic Models: Impact of Enzyme Maturation Versus Inhibition.

CPT Pharmacometrics Syst Pharmacol · 2019 · PMC6430158 · PMID 30520273

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may not be significantno p-value reported

19 The effect of P‐gp on absorption is not considered in our current model due to the limited data regarding transporter maturation, and the contribution of P‐gp to absorption may not be significant because pantoprazole is a high permeability compound.

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