Changes in the functions of the respiratory chain in lung tissue The changes in the functions of respiratory chain complexes I, IV and V and the changes in copy number of the corresponding mtDNA-encoded genes were similar in the tissues at 4, 8 and 24 weeks after radiation exposure; the changes were the greatest at 8 weeks and then displayed a decreasing trend until 24 weeks.
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Oxidative stress levels and dynamic changes in mitochondrial gene expression in a radiation-induced lung injury model.
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