highly significantP < 1 × 10 −4
The breadth of the responses to the 11 epitopes showed highly significant correlations with both lower pVLs ( P < 1 × 10 −4 ; r = −0.4909) and higher CD4 counts ( P < 1 × 10 −4 ; r = 0.4542) in these Japanese individuals ( Fig. 8B ).