borderline significantP = 0.052
In a univariable analysis, global stress MBF also decreased with increasing EDVI (estimate − 0.10 (ml/g/min) per (10 ml/m 2 ); P < 0.0001), but with multivariable adjustment the decrease was only borderline significant (estimate − 0.06 (ml/g/min) per (10 ml/m 2 ); P = 0.052).