Formation of a morphine-conditioned place preference does not change the size of evoked potentials in the ventral hippocampus-nucleus accumbens projection.

Analysis of the first 15-min time-window only, the point at which morphine-induced locomotion was typically largest, revealed a highly significant drug × day interaction [F(3,18) = 7.35; p = 0.002], reflecting the widening difference between saline and drug days as conditioning progressed: activity increased across morphine days, but decreased across saline days.

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