Hydrophobicity, rather than secondary structure, is essential for the SRP dependent targeting of GPR35 to the ER membrane.

J Bioenerg Biomembr · 2019 · PMC6439181 · PMID 30706279

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a possible trendno p-value reported

This suggested that the first TM domain of Bop traversed the ribosome in an unstructured state, eluding to a possible trend in seven TM domain proteins.

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