Barely Significant
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Prevalence of <i>Helicobacter pylori</i> infection in Sari Northern Iran; a population based study.

Gastroenterol Hepatol Bed Bench · 2019 · PMC6441486 · PMID 30949317

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a decreasing trendno p-value reported
But by having more than 11000 samples, there was a decreasing trend in time in studies from 1993 to 2010.

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an obvious trendno p-value reported
An obvious trend could be seen in the samples based on their age groups and there was a significant correlation between seropositivity for IgG antibody of Helicobacter pylori and the age groups (p=0.001).

also in 1,006 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.