Smoking, Alcohol Consumption, and Risks for Biliary Tract Cancer and Intrahepatic Bile Duct Cancer.

J Epidemiol · 2019 · PMC6445799 · PMID 29760302

Europe PMC DOI

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marginally significantno p-value reported

Current smokers with ≥30 pack-years had a non-significant trend of increased BTC risk compared with non-smokers among non-/occasional drinkers (HR 1.64; 95% CI, 0.94–2.86) but not among regular drinkers, and the interaction was marginally significant ( P -interaction = 0.023).

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a nonsignificant trendno p-value reported

It is interesting that different effects of smoking were observed between IHBDC and BTC when stratified by drinking status; a nonsignificant trend of increased risk of BTC in non-/occasional drinkers and no association in regular drinkers, while we found increased risk of IHBDC in regular drinkers and no association in no/occasional drinkers.

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