Presynaptic α<sub>2</sub>δ-2 Calcium Channel Subunits Regulate Postsynaptic GABA<sub>A</sub> Receptor Abundance and Axonal Wiring.

This finding was further corroborated by a highly significant reduction of the mean distance from the contacting presynaptic boutons to the postsynaptic dendritic shafts in α 2 δ-2-transfected compared with control axons (mean distance ± SEM: control: 0.92 ± 0.05 μm; α 2 δ-2: 0.54 ± 0.05 μm; Mann–Whitney U test: p < 0.001; Fig. 11 C , bottom).

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