Determinant roles of dendritic cell-expressed Notch Delta-like and Jagged ligands on anti-tumor T cell immunity.

J Immunother Cancer · 2019 · PMC6446314 · PMID 30940183

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highly significantno p-value reported

The analysis revealed a highly significant correlation between the proportion of JAG1 or JAG2-expressing tissue-resident CD11b + CD11c high DCs and the numbers of PD-1-expressing T-effector-memory (Tem) CD8 + CCR7 − CD45RA − and T-terminal-effector (Temra) CD8 + CCR7 − CD45RA + cells, with JAG1 demonstrating the strongest correlation ( p = 0.0005) (Fig. 7 b and Additional file 3 : Figure S3).

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