Targeting MAPK phosphorylation of Connexin43 provides neuroprotection in stroke.

J Exp Med · 2019 · PMC6446879 · PMID 30872361

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a nonsignificant trendno p-value reported

Consistent with MAPK phosphorylation levels, WT astrocytes exposed for 3 h to ischemic buffer in high (27 mM) glucose plus hypoxia (<1% O 2 ) showed a nonsignificant trend toward higher phosphorylation levels at Cx43 sites Ser-279 and Ser-282 compared with media controls ( Fig. 4 E ).

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