The predictive and prognostic value of baseline CD positivity at the invasive tumor margin has been evaluated in part A of JAVELIN Merkel 200, and a nonsignificant trend toward higher response rate and longer OS with higher tumor CD8 + levels was observed, but given the small sample, the presence of tumor responses across all evaluated subgroups cannot be described as predictive or prognostic [ 34 ].
← all excerpts
Early objective response to avelumab treatment is associated with improved overall survival in patients with metastatic Merkel cell carcinoma.
1
—
—