Barely Significant
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Ultra-low dose one-step CT angiography for coronary, carotid and cerebral arteries using 128-slice dual-source CT: A feasibility study.

Exp Ther Med · 2019 · PMC6447913 · PMID 30988794

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a decreasing trendno p-value reported
However, a low concentration and volume of the contrast agent were used for CTA, resulting in a decreasing trend in the time density curve (TDC), which affected the arterial enhancement.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.