Barely Significant
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Independent validation of tumour volume, cancer stem cell markers and hypoxia-associated gene expressions for HNSCC after primary radiochemotherapy.

Clin Transl Radiat Oncol · 2019 · PMC6449705 · PMID 30993218

2
hedged sentences
0.0080
closest p · 0.2× alpha
0.0840
boldest claim

The sentences

borderline significancep = 0.008actually significant
2 C, D) could not be validated as a significant prognostic factor for LRC, while the total volume of primary tumour and lymph nodes showed borderline significance for LRC in the validation set (t: HR = 1.57, p = 0.008; v: HR = 1.61, p = 0.050).

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a statistical trendp = 0.084so close (0.05 < p ≤ 0.1)
The 2-year rates of LRC were similar between both cohorts (LRC: 62.6% vs 64.1%, p = 0.62), while, as a statistical trend, OS was higher in the training cohort (59.6% vs 53.2%, p = 0.084).

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