When we used 10mM glucose, where HKs are saturated and the contribution of GK to the phosphorylating activity is higher, we observed a highly significant decrease on the phosphorylation activity only in Ad-GKRP-transduced cells ( Figure 2A ).
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When a Little Bit More Makes the Difference: Expression Levels of GKRP Determines the Subcellular Localization of GK in Tanycytes.
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